Main Results

-Publications:

Vélez, E. J., Schnebert, S., Goguet, M., Balbuena-Pecino, S., Dias, K., Beauclair, L., … Seiliez, I. (2023). Chaperone-mediated autophagy protects against hyperglycemic stress. Autophagy, 20(4), 752–768. https://doi.org/10.1080/15548627.2023.2267415

Author Accepted Manuscript (AAM) available at: https://hal.inrae.fr/hal-04231578

Associated dataset available at: https://doi.org/10.57745/DWDYN0

Emilio J. Vélez, Vincent Véron, Jeanne Gouis, Steffi Reji, Karine Dias, Amaury Herpin, Florian Beaumatin, Iban Seiliez (2024). Endosomal Microautophagy is Activated by Specific Cellular Stresses in Trout Hepatocytes. bioRxiv 2024.09.26.615173;  https://doi.org/0.1101/2024.09.26.615173  

Associated dataset available at: https://doi.org/10.5745/K4XF9I 

- Other datasets:

Data generated by MEAL fish project - 1/2 :  https://doi.org/10.57745/HCAZCG

Data generated by MEAL fish project - 2/2 : https://doi.org/10.57745/DDNRLG

- Main Dissemination & Communication Activities:

- Oral presentation of MEAL fish project at the NuMeA monthly scientific meeting (St-pee, September 2022)

- Oral presentation of first results/plan at the Aquaexcel3.0 annual meeting (Heraklion, Greece, October 2022). 

AUTHORS: Vélez, E.J., Schnebert, S., Goguet, M., Balbuena-Pecino, S., Dias, K., Beauclair, L., Véron, V., Beaumatin, F., Herpin, A. and Seiliez, I.  
TITLE: First in vitro assessment of Chaperone-Mediated Autophagy (CMA) and its metabolic implications in rainbow trout hepatocytes.

- Oral presentation of first results at the SEFAGIA (Sociedad Española de Autofagia) 2022 meeting in Toledo, Spain. (11/2022)   https://x.com/SEFAGIA_/status/1591043887422111744 

AUTHORS: Vélez, E.J., Schnebert, S., Goguet, M., Balbuena-Pecino, S., Dias, K., Beauclair, L., Véron, V., Depincé, A., Beaumatin, F., Herpin, A. and Seiliez, I.  
TITLE: Dissecting the regulation of CMA in a natural model of impaired glucose homeostasis, the rainbow trout.

- Oral presentation at the Séminaire Poissons INRAE (Rennes, France, January 2023) 

AUTHORS: Vélez, E.J., Schnebert, S., Goguet, M., Dias, K., Beauclair, L., Véron, V., Beaumatin, F., Herpin, A. and Seiliez, I.  
TITLE: Lighting Chaperone-Mediated Autophagy in fish.

- Oral presentation of results at MetaBoDay 2023 conference (Talence, France, May 2023)    *Best Oral Presentation (post-docs) 

AUTHORS: Vélez, E.J., Schnebert, S., Goguet, M., Balbuena-Pecino, S., Dias, K., Beauclair, L., Véron, V., Depincé, A., Beaumatin, F., Herpin, A. and Seiliez, I.  
TITLE: Fishing for clues of the role of Chaperone-Mediated Autophagy in hyperglycemia-induced stress.

- MEAL fish project presentation at the Journee Portes Ouvertes of Aquapole INRAE, in Saint-Pée-sur-Nivelle (11/6/2023) https://x.com/MealFish/status/1667776069443698689

- Oral presentation of MEAL fish results at Aquaculture Europe 2023 conference in Vienna, Austria (09/2023) https://x.com/MealFish/status/1704734519973007840 

AUTHORS: Vélez, E.J., Schnebert, S., Goguet, M., Balbuena-Pecino, S., Dias, K., Beauclair, L., Fontagné-Dicharry, S., Véron, V., Depincé, A., Beaumatin, F., Herpin, A. and Seiliez, I.  
TITLE: Dissecting the role of chaperone-mediated autophagy in the intolerance to carbohydrates of the rainbow trout (Oncorhynchus mykiss).

- Oral presentation of MEAL fish results at the CFATG11 – 11th Scientific Days on Autophagy (The Francophone Autophagy Club) conference in Lyon, France. (11/2023)  https://x.com/seiliez2/status/1722557152118624575   *Travel grant received 

AUTHORS: Vélez, E.J., Schnebert, S., Goguet, M., Balbuena-Pecino, S., Dias, K., Beauclair, L., Fontagné-Dicharry, S., Véron, V., Depincé, A., Beaumatin, F., Herpin, A. and Seiliez, I.  
TITLE: Chaperone-Mediated Autophagy safeguards against hyperglycemic stress.

- Wrapping up meeting at the NuMeA monthly scientific seminars (St-pee, September 2024)

Featured in the Media & Interviews:

- 10/10/2023: Stress hyperglucidique: découverte d’un mécanisme de protection. INRAE press release.  https://bit.ly/CMAsweet

- 11/10/2023: Brèves; Stress hyperglucidique : découverte d’un mécanisme de protection. La GAZETTE DU LABORATOIRE. https://bit.ly/gazetteCMA   

- 12/10/2023: Trop de sucre dans le sang ? Le stress "hyperglucidique" vous guette peut-être.  Le Journal des Femmes. https://bit.ly/journaldesfemmesCMA

- 12/10/2023: Un mécanisme cellulaire complexe contre le stress hyperglucidique. Nutrition365. https://bit.ly/nutrition365CMA 

- 13/10/2023: Qu'est-ce que le "stress hyperglucidique" qui menace quand on a trop de sucre dans le sang ? Le Journal des femmes. Aufeminin. https://bit.ly/aufemininCMA 

- 01/11/2023: Quand des cellules de la truite s’autodévorent pour se préserver. Le Monde. https://bit.ly/LeMondeCMA 

- 29/11/2023: Stress hyperglucidique : découverte d’un mécanisme de protection crucial. Université de Pau et des Pays de l'Adour (UPPA). https://bit.ly/UniPauCMA 

MEAL fish is supported by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101030643